MEK versus Iran

2025-01-11 08:53:04 | mek

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• 2025-01-10 17:48 MEK inhibitor IMM-1-104 shows promise in pancreatic cancer: Data - Myeloma Research News
• 2025-01-07 12:02 Immuneering Announces Positive Data Update from Three - GlobeNewswire
• 2025-01-07 16:13 Immuneering touts positive pancreatic cancer data for MEK inhibitor - Endpoints News
• 2024-12-12 19:30 DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells - ScienceDirect.com
• 2024-09-09 07:00 Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage - Nature.com
• 2024-06-26 07:00 MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells - Science
• 2024-06-30 14:33 MEK Inhibition in a Pilocytic Astrocytoma With a Rare KRAS Q61R Mutation in a Young Adult Patient: A Case Report - ASCO Journals
• 2024-06-20 07:00 MEK Leaders May Be Extradited to Iran, Judiciary Official Says - ایران اینترنشنال
• 2024-07-01 09:39 MEK inhibitors: a promising targeted therapy for cardiovascular disease - Frontiers
• 2024-11-15 08:00 Long-Term Outcomes of BRAF-MEK Inhibitor Combinations - OncLive
• 2024-10-22 07:00 MEK inhibition prevents CAR-T cell exhaustion and differentiation via downregulation of c-Fos and JunB - Nature.com
• 2024-12-11 08:00 Second MEK Inhibitor Shows Promise in Neurofibromatosis Type 1 With Symptomatic Plexiform Neurofibromas Signaling Hope for Other RASopathies - ASCO Journals
• 2024-12-02 08:00 MEK Inhibitors Strategic Business Research Report - GlobeNewswire
• 2024-05-01 07:00 Effect of NFX-179 MEK inhibitor on cutaneous neurofibromas in persons with neurofibromatosis type 1 - Science
• 2024-09-05 07:06 Echinatin alleviates sepsis severity through modulation of the NF-κB and MEK/ERK signaling pathways - ScienceDirect.com
• 2024-12-18 08:00 The clinically relevant MEK inhibitor mirdametinib combined with D-cycloserine and prediction error disrupts fear memory in PTSD models - Nature.com
• 2024-12-12 08:00 Choosing Between Anti–PD-1 Therapy or BRAF/MEK Inhibitors in Stage III BRAF-Mutated Melanoma - ASCO Daily News
• 2024-09-05 07:00 Efficacy of PARP inhibitor therapy after targeted BRAF/MEK failure in advanced melanoma | npj Precision Oncology - Nature.com
• 2024-05-15 07:00 Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies - Nature.com
• 2024-02-22 08:00 The CNK–HYP scaffolding complex promotes RAF activation by enhancing KSR–MEK interaction - Nature.com
• 2024-11-11 08:00 Abstract 4120743: MEK inhibition for recurring pulmonary valve stenosis in RASopathy patients - AHA Journals
• 2024-06-21 07:36 Apigenin potentiates glucose-stimulated insulin secretion through the PKA-MEK kinase signaling pathway independent of K-ATP channels - ScienceDirect.com
• 2024-04-06 07:00 The prognostic value of MEK pathway–associated estrogen receptor signaling activity for female cancers - Nature.com
• 2024-04-10 07:00 CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma | Scientific Reports - Nature.com
• 2024-05-20 07:00 Dr Salani on Research With MEK Inhibition in KRAS-Mutant Serous Ovarian Cancer - OncLive
• 2024-07-30 04:07 MEK’s shadow in European Parliament - Responsible Statecraft
• 2024-03-21 07:00 The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression - Nature.com
• 2024-05-31 07:00 Exceptional Response of BRAFV600E-Mutated Acinar Cell CUP to BRAF/MEK Inhibition | JCO Precision Oncology - ASCO Journals
• 2024-02-26 08:00 Concurrent inhibition of pBADS99 synergistically improves MEK inhibitor efficacy in KRAS - Nature.com
• 2024-08-28 07:00 Erratum for the Research Article “MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells” by S. Perrin et al - Science
• 2024-11-12 08:00 TIPE2 inhibits melanoma progression through MEK/ERK signaling - Nature.com
• 2024-05-31 07:00 Exceptional Response of BRAFV600E-Mutated Acinar Cell CUP to BRAF/MEK Inhibition | JCO Precision Oncology - ASCO Journals
• 2024-05-24 18:45 The natural compound ugonin V targets MMP7 production and restricts chondrosarcoma metastasis by suppressing the MEK/ERK/c-Jun signaling pathways - ScienceDirect.com
• 2024-11-20 08:00 Study Compares Skin Toxicities of MEK Inhibitors in Children - Medscape
• 2024-06-23 07:00 MEK-inhibitor treatment reduces the induction of regulatory T cells in mice after influenza A virus infection - Frontiers
• 2024-12-13 11:26 Extension for the Project on the Sámi Collection at MEK until November 2025 - Staatliche Museen zu Berlin
• 2024-07-19 07:00 USP32 facilitates non-small cell lung cancer progression via deubiquitinating BAG3 and activating RAF-MEK-ERK signaling pathway - Nature.com
• 2024-12-31 20:22 Vietnamese monk leaves Laos, enters Thailand - Radio Free Asia
• 2024-09-02 11:49 Muslim InVisibilities at the Museum Europäischer Kulturen (MEK) - Staatliche Museen zu Berlin
• 2024-09-22 07:00 MEK Menopause Special Focus Day on 22 September 2024: It’s far from over! - Staatliche Museen zu Berlin
• 2024-04-08 14:14 Áimmuin: Re-Connecting Sámi Heritage - Staatliche Museen zu Berlin
• 2024-09-11 07:00 Clinical Mic Drop: The Latest Innovations on MEK Therapies for Neurofibromatosis Type 1-Associated Plexiform Neurofibromas - PRIME® Continuing Medical Education
• 2024-08-21 07:00 ZOTAC GAMING Reveals MEK HERO Gaming PC Deals at Amazon This August Starting at Just $1,011.39 - PR Web
• 2024-04-25 07:00 TMEM9 promotes lung adenocarcinoma progression via activating the MEK/ERK/STAT3 pathway to induce VEGF expression - Nature.com
• 2024-02-15 07:26 Combined inhibition of MEK and Aurora A kinase in KRAS PIK3CA double-mutant colorectal cancer models - Frontiers
• 2024-11-08 08:00 Activation of MEK‐ERK‐c‐MYC signaling pathway promotes splenic M2-like macrophage polarization to inhibit PHcH-liver cirrhosis - Frontiers
• 2024-08-23 00:42 The Küppers Collection at MEK - Staatliche Museen zu Berlin
• 2024-03-20 07:00 Erratum for the Research Article “Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers,” by C. Sun et al - Science
• 2024-02-29 08:00 Cysteine protease inhibitor 1 promotes metastasis by mediating an oxidative phosphorylation/MEK/ERK axis in esophageal squamous carcinoma cancer - Nature.com
• 2024-01-22 08:00 A MEK inhibitor arrests the cell cycle of human conjunctival fibroblasts and improves the outcome of glaucoma filtration surgery - Nature.com
• 2024-08-22 10:20 Online Presentation: Traces of European Muslims in the MEK Collection - Staatliche Museen zu Berlin
• 2024-02-05 16:19 Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma - Frontiers
• 2024-02-13 18:10 Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance - Frontiers
• 2024-01-21 08:00 Dual inhibition of MEK and PI3Kβ/δ–a potential therapeutic strategy in PTEN-wild-type docetaxel-resistant metastatic prostate cancer - Frontiers
• 2020-06-16 07:00 Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers - ScienceDirect.com
• 2018-11-09 08:00 Terrorists, cultists – or champions of Iranian democracy? The wild wild story of the MEK - The Guardian
• 2023-07-12 07:00 BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas - nejm.org
• 2020-03-22 07:00 Defectors Tell of Torture and Forced Sterilization in Militant Iranian Cult - The Intercept
• 2012-06-04 07:00 Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma - nejm.org
• 2012-12-21 08:00 Canada drops Iranian group MEK from terror list - CBC.ca
• 2022-04-07 07:00 MEK and MCL-1 sequential inhibition synergize to enhance rhabdomyosarcoma treatment - Nature.com
• 2014-09-29 07:00 Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma - nejm.org
• 2021-03-30 07:00 PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK - ScienceDirect.com
• 2018-03-29 07:00 MEK’s violent past looms over US lobby for regime change in Iran - Al Jazeera English
• 2024-01-18 08:00 Rapid diurnal variation of serous retinal detachment during BRAF and MEK inhibitor treatment: A case series - Wiley Online Library
• 2024-02-16 16:53 Pharmacokinetics, absorption, distribution, metabolism and excretion of the MEK inhibitor zapnometinib in rats - Frontiers
• 2022-07-14 07:00 Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression - Nature.com
• 2022-07-16 07:00 Iran blacklists US officials for supporting ‘terrorist’ group MEK - Al Jazeera English
• 2022-11-23 08:00 MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression - Nature.com
• 2016-12-13 08:00 Yes, We Do Know the MEK Has a Terrorist Past - POLITICO
• 2020-12-17 08:00 MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axes - Nature.com
• 2020-09-08 07:00 MEK Inhibitors for the Treatment of Low-Grade Serous Ovarian Cancer: Expanding Therapeutic Options for a Rare Ovarian Cancer Subtype | Journal of Clinical Oncology - ASCO Journals
• 2019-03-13 07:00 Efficacy of MEK inhibition in patients with histiocytic neoplasms - Nature.com
• 2020-11-23 08:00 T lymphocytes into memory stem cells with potent antitumor effects - Nature.com
• 2014-07-28 07:00 Mujahadeen-e-Khalq (MEK) - Council on Foreign Relations
• 2021-09-01 01:33 Targeting enhancer reprogramming to mitigate MEK inhibitor resistance in preclinical models of advanced ovarian cancer - JCI
• 2023-07-03 07:00 Iran condemns MEK rally in France as support for ‘terrorism’ - Al Jazeera English
• 2018-07-02 07:00 Who is the Iranian group targeted by bombers and beloved of Trump allies? - The Guardian
• 2023-06-20 07:00 Albanian Police Raid Iranian Opposition MEK Camp | Iran International - ایران اینترنشنال
• 2023-10-30 07:00 Former MEK leader Massoud Rajavi died under US guard, say Iran media - Al Jazeera English
• 2023-04-06 07:00 MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ - Nature.com
• 2019-05-16 07:00 MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer - Nature.com
• 2023-06-21 07:00 Why was this Iran dissident group raided in Europe? - Al Jazeera English
• 2018-05-07 07:00 M.E.K.: The Group John Bolton Wants to Rule Iran (Published 2018) - The New York Times
• 2021-02-12 08:00 Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor - Nature.com
• 2018-10-19 07:00 Targeting MEK in vemurafenib-resistant hairy cell leukemia - Nature.com
• 2023-11-13 23:17 Bruceine A: Suppressing metastasis via MEK/ERK pathway and invoking mitochondrial apoptosis in triple-negative breast cancer - ScienceDirect.com
• 2013-09-26 07:00 Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma - ScienceDirect.com
• 2022-11-22 08:00 Triple blockade of Ido-1, PD-L1 and MEK as a potential therapeutic strategy in NSCLC - Journal of Translational Medicine
• 2018-08-20 07:00 Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells - Nature.com
• 2017-12-31 14:20 Murine Ksr interacts with MEK and inhibits Ras-induced transformation - ScienceDirect.com
• 2019-12-09 08:00 MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia - Nature.com
• 2023-10-13 07:00 MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling - Nature.com
• 2018-07-18 07:00 PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells - Science
• 2015-06-05 07:00 MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicity - Nature.com
• 2022-06-02 07:00 Head-to-head comparison of the dual-MEK inhibitor IMM-1-104 versus sotorasib or adagrasib in KRAS mutant pancreatic tumors. - ASCO Journals
• 2023-05-25 07:00 Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma - Nature.com
• 2020-10-09 07:00 Chemical profile: US MEK - ICIS
• 2022-03-10 08:00 Trametinib to Treat Low-Grade Serous Ovarian Cancer - NCI Cancer Bulletin
• 2021-09-08 10:29 Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers - Science

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MEK versus Iran

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